6.  FIRE & EXPLOSION HAZARD DATA

Flammable Properties
Flash Point (ASTM D-92)                                                      246º (119ºF)

FLAMMABILITY LIMITS - % of vapor concentration at which product can ignite in presence of spark
Lower Flammability Limit:  3.2%
Upper Flammability Limit:  15.3%

Extinguishing Media                                      Foam, CO₂ gas, dry chemical, and water fog
Fire Fighting Procedures                             Avoid inhalation of smoke
Fire and Explosion Hazards                          None

7.  REACTIVITY DATA

Stability                                                          Stable
Conditions to Avoid                                       Keep away from flame
Incompatibility (Materials to Avoid)          Strong acid or oxidizing agents
Hazardous Decomposition Products          Incomplete combustion may produce CO gas
Hazardous Polymerization                          Will not occur

8.  HEALTH & HAZARD DATA

Inhalation, Skin, Ingestion:   May cause skin, eye and mucous membrane irritation.  Inhalation of high concentrations of mist or vapors may cause nausea, CNS depression, lethargy.  (CNS: Central Nervous System)

Signs and Symptoms of Exposure: Skin, eye and mucous membrane irritation, lethargy, nausea, defatting of skin, CNS depression.

 Emergency and First Aid Procedures: In case of skin and eye contact, flush thoroughly with water, if necessary go to hospital.  If swallowed, induce vomiting, call a physician. 

Steps to be Taken in Case Material is Released or Spilled: Eliminate all sources of ignition in the vicinity of spilled or released fluid. 

Waste Disposal Method: Use absorbent material such as clothing.  Clean up spill and dispose of contaminated material in approved disposal site or incinerator. 

9.  PRECAUTIONS FOR HANDLING AND STORAGE 

Steps to be Taken in Case Material is Released or Spilled: Eliminate all sources of ignition in vicinity of the spilled or released fluid. 

Other Precautions: Use normal precautions in handling any combustible liquid.  Keep container closed when not in use.  Store away from heat or open flame. 

                   10.  EXPOSURE CONTROLS / PERSONAL PROTECTION 

Respiratory Protection:   Respiratory protection is required if airborne concentration exceeds TLV.  At any  detectable concentration, any self-contained breathing apparatus with a full facepiece and operated in a pressure-demand or other positive pressure mode or any supplied-air respirator with a full facepiece and operated in a pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode.

Escape:                   Any air-purifying full facepiece respirator (gas mask) with a chin-style or front- or back-mounted organic vapor canister or any appropriate escape-type self-contained breathing apparatus. 

Skin Protection: Protective gloves recommended when prolonged skin contact cannot be avoided.  Polyethylene; Neoprene; Nitrile; Polyvinyl alcohol; Natural Rubber, Butyl Rubber.  Safety shower should be available. 

Eye Protection: Safety goggles and face shield.  Emergency eyewash should be available.  Contact lenses should not be worn when working with this chemical. 

Engineering Controls:  Use general or local exhaust ventilation to meet TLV requirements.

EXPOSURE LIMITS 

Component                                      Exposure Limits                                      Skin Form

 Ethylene glycol                     100mg/m3 CEILING ACGIH                            Aerosol

Ethylene glycol                      125 mg/m3 CEILING OSHA-vacated

                                                    50 ppm CEILING OSHA – vacated

                                                 100 mg/m3 CEILING UCC                                Aerosol and Vapor

Diethylene glycol                  50 ppm TWA8 AIHA WEEL                          Aerosol and Vapor

Diethylene glycol                  10 mg/m3 TWA8 AIHA WEEL                      Aerosol

In the Exposure Limits Chart above, if there is no specific qualifier (i.e., Aerosol) listed in the Form Column for a particular limit, the listed limit includes all airborne forms of the substance that can be inhaled.

 A “Yes” in the Skin Column indicates a potential significant contribution to overall exposure by the cutaneous (skin) route, including mucous membranes and the eyes, either by contact with vapors or by direct skin contact with the substance.  A “Blank” in the Skin column indicates that exposure by the cutaneous (skin) route is not a potential significant contributor to overall exposure.

11.  CONTROL MEASURES

 Respiratory Protection  (Specify Type)                             Not necessary

Ventilation:          Local Exhaust                                            Not necessary
                       Mechanical (General)                                Normal ventilation
                       Special                                                         Not necessary
                       Other                                                            Not necessary

 Protective Gloves:                                                                   Necessary 

Eye Protection:                                                                         Safety goggles

12.  TOXICOLOGICAL INFORMATION

SKIN:                           The dermal LD50 has not been determined. 
INGESTION:              The lethal dose in humans is estimated to be 100 ml (3 ounces).  The oral LD50 for rats is in the 6000-13,000-mg/kg range.

Hydrated Inorganic Acid Sodium Salt:  The lowest dose of a similar compound reported to produce death in humans was estimated to be 709 mg/kg body weight for a person weighing 150 pounds, this would be equivalent to swallowing about one-tenth (.1) of a pound of the dry material in a short period of time.

 Acute oral LD50s

 For a similar compound      =                                                   2,650 mg/kg (rats)                                                                                                      2,000 mg/kg (mice)

MUTAGENICITY (THE EFFECTS ON GENETIC MATERIAL):  In vitro mutagenicity studies were negative.  Animal mutagenicity studies were negative.

 SIGNIFICANT DATA WITH POSSIBLE RELEVANCE TO HUMANS
Ethylene glycol has been shown to produce dose-related teratogenic effects in rats and mice when given by gavage or in drinking water at high concentrations or doses.  The no-effect doses for developmental toxicity for ethylene glycol given by gavage over the period of organogenesis has been shown to be 150 mg/kg/day for the mouse and 500 mg/kg/day for the rat.  Also, in a preliminary study to asses the effects of exposure of pregnant rats and made to aerosis at concentrations of 150, 1000 and 25000 mg/m3 for 6 hours a day throughout the period of organogenesis, teratogenic effects were produced at the highest concentration, but only in mice.  The conditions of these latter experiments did not allow a conclusion as to whether the developmental toxicity was mediated by inhalation of aerosol percutaneous absorption of ethylene glycol from contaminated skin, or swallowing ethylene glycol as a result of grooming the wetted coat.  In a further study, comparing effects from high aerosol concentration by whole-body or nose-only exposure, it was shown that nose-only exposure resulted in maternal toxicity (1000 and 25000 mg/m3) and developmental toxicity with minimal evidence of teratogenicity (2500 mg/m3).  The no-effects concentration (based on maternal toxicity) was 500 mg/m3.  In a further study in mice, no teratogenic effects could be produced when ethylene glycol was applied to skin of pregnant mice over the period of organogenesis.  The above observations suggest that ethylene glycol is to be regarded as an animal teratogen.  There is currently no available information to suggest that ethylene glycol has caused birth defects in humans.  Cutaneous application of ethylene glycol is ineffective in producing developmental toxicity.  Exposure to high aerosol concentrations is only minimally effective in producing developmental toxicity.  The major route for producing developmental toxicity is perorally.  Two chronic feeding studies, using rats and mice, have not produced any evidence that ethylene glycol causes dose-related increases in tumor incidence or a different pattern of tumors compared with untreated controls.  The absence of carcinogenic potential for ethylene glycol has been supported by numerous in vitro genotoxicity studies showing that it does not produce mutagenic or clastogenic effects.

A chronic dietary feeding study of diethylene glycol with rats showed mild kidney injury at 1%, while concentrations of 2% and 4% caused more marked kidney injury.  In addition, at 2% and 4% of diethylene glycol in the diet, some rats developed benign papillary tumors in the urinary bladder.  These have been attributed to the presence of urinary bladder calcium oxalate stones.  No evidence for carcinogenicity was found with a chronic skin-painting study with diethylene glycol in mice.  The absence of a direct chemical carcinogenic effect addords with the results in vitro genotoxicity studies that show that it does not produce mutagenic or clastogenic effects.  A feeding study employing up to 5.0% diethylene glycol in the diet failed to produce any teratogenic effects.  In a mouse continuous breeding study with large doses of diethylene glycol in drinking water, there was evidence for reproductive toxicity at 3.5% (equivalent to 6.1 g/kg/day) as reduced number of litter, live pups per litter and live pup weight.  No such effects were seen at 1.75% (approximately 3.05 g/kg/day).  The relevance of these very high dosages to human health is uncertain.  Pregnant rats receiving undiluted diethylene glycol by gavage over the period of organogenesis had toxic effects at 4.0 and 8.0 ml/kg/day as mortality, decreased body weight, decreased food consumption increased water consumption and increased liver and kidney weights.  Fetotoxicity was seen only at these maternally toxic dosages.  Decreased fetal body weight occurred at 8.0 ml/kg/day, and increased skeletal variants at 4.0 and 8.0 ml/kg/day.  No embryotixic or teratogenic effects were seen.  Neither maternal toxicity nor fetotoxicity occurred at 1.0 ml/kg/day.  In a study with mice also receiving undiluted diethylene glycol over the period of organogenesis, maternal toxicity occurred at 2.5 and 10.0 ml/kg/day, but not at 0.5 ml/kg/day.  Definitive developmental toxicity was not seen in this species.

13.  ECOLOGICAL INFORMATION 

ENVIRONMENTAL FATE

MOVEMENT & PARTITIONING:  Bioconcentration potential is low (BCF less than 100 or Log Kow less than 3).  Log octanol/water partition coefficient (log Kow) is -1.36.  Henry's Law Constant (H) is 6.0E-08 atm-m3/mol.  Bioconcentration factor (BCF) is 10 in golden orfe. 

DEGRADATION & TRANSFORMATION:  Biodegradation under aerobic static laboratory conditions is high (BOD20 or BOD28/ThOD greater than 40%).  5-Day biochemical oxygen demand (BOD5) is 0.78 p/p.  10-Day biochemical oxygen demand (BOD10) is 1.06 p/p.  20-Day biochemical oxygen demand (BOD20) is 1.15 p/p.  Theoretical oxygen demand (ThOD) is calculated to be 1.29 p/p.  Biodegradation may occur under both aerobic and anaerobic conditions (in either the presence or absence of oxygen).  Inhibitory concentration (IC50) in OECD "Activated Sludge, Respiration Inhibition Test" (Guideline # 209) is < 1000 mg/L.  Degradation is expected in the atmospheric environment within days to weeks.

 ECOTOXICOLOGY:  Material is practically non-toxic to aquatic organisms on an acute basis (LC50 greater than 100 mg/L in most sensitive species).  Acute LC50 for fathead minnow (Pimephales promelas) is 51000 mg/L.  Acute LC50 for bluegill (Lepomis macrochirus) is 27549 mg/L.  Acute LC50 for rainbow trout (Oncorhynchus mykiss) is about 18000-46000 mg/L.  Acute LC50 for guppy (Poecilia reticulata) is 49300 mg/L.  Acute LC50 for water flea (Daphnia magna) is 46300-51100 mg/L.  Acute LC50 for the cladoceran Ceriodaphnia dubia is 10000-25800 mg/L.  Acute LC50 for crayfish is 91430 mg/L.  Acute LC50 for brine shrimp (Artemia salina) is 20000 mg/L.  Acute LC50 for golden orfe (Leuciscus idus) is greater than 10000 mg/L.  Acute LC50 for goldfish (Carassius auratus) is greater than 5000 mg/L.  Growth inhibition EC50 for green alga Selenastrum capricornutum is 9500-13000 mg/L. 

14.  DISPOSAL CONSIDERATIONS 

DO NOT discharge to sewer.  Wear appropriate personal protection.  Take up with sand, vermiculite, or similar inert material.  Dispose in accordance with federal, state and local regulations.

 15.  TRANSPORT INFORMATION

U.S. D.O.T.   NON-BULK Proper shipping name:  BULK Proper shipping name: Technical name:  ID Number: Hazard Class: Packing Group: ReportableQuantity:  IATA  NON-BULK Proper Shipping Name: Not Regulated by IATA

ETHYLENE GLYCOL ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID N.O.S. (ETHYLENE GLYCOL) E THYLENE GLYCOL   UN3082 9 PG III   5,000 lb. Ethylene Glycol

 16.  REGULATORY INFORMATION

 THIS PRODUCT CONTAINS COMPONENT(S) CITED ON THE FOLLOWING REGULATIONS: 

CHEMICAL NAME                                   CAS NUMBER
                                                  Ethylene Glycol                                                 107-21-1
UNITED STATES

TSCA - Inventory:                                 Listed

 WATER STANDARDS:                      No data available

 ATMOSPHERIC STANDARDS:      Clean Air Act (1990) - List of Hazardous Air Contaminants: listed

 CERCLA:                                               Reportable Quantity (RQ): 5,000 pounds (532 gallons)

 SARA Title III:                                      Section 311/312 - Categories: Acute hazard; chronic hazard

 Section 312 - Inventory Reporting: Ethylene glycol is subject to Tier I and/or Tier II annual inventory reporting

 Section 313 - Emission Reporting: Ethylene glycol is subject to Form R reporting requirements

 Section 302 - Extremely Hazardous Substances: Ethylene glycol is not listed

STATE RIGHT-TO-KNOW:

California Exposure Limits - Ceilings                               Vapor-50ppm ceiling; 125 mg/m3 ceiling
Florida Hazardous Substances List                                   Listed
Massachusetts Right-to-Know List                                  Listed
Minnesota Hazardous Substance List                              Listed (particulate and vapor)
New Jersey Right-to-Know List (Total)                            Present greater than 1.0%
Pennsylvania Right-to-Know List                                     Environmental hazard

CANADIAN REGULATION:

WHMIS Information:  The Canadian Workplace Hazardous Materials Information System (WHMIS) classification for this product is:

D2A - material has potential toxic effects.   Refer elsewhere in the MSDS for specific warnings and safe handling information.  Refer to the employer’s workplace education program.

 California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986)  This product contains the following chemical(s) known to the State of California to cause cancer:

Component                                                   CAS #                                                      Amount

1,4 – Dioxane                                                123-91-1                                                    <=0.0086%
Acetaldehyde                                               75-07-0                                                     <=0.1000PPM

 California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986) 
 This product contains the following chemical(s) known to the State of California to cause birth defects and/or other reproductive harm.

Component                                                   CAS #                                                      Amount

Ethylene glycol monomethyl ether           109-86-4                                                 <=0.0009%

 California SCAQMD Rule 443.1 (South Coast Air Quality Management District Rule 443.1, Labeling of Materials Containing Organic Solvents)

VOC:  Vapor pressure 0.06 mmHg at 20°C

1113.38 g/l

 17.  OTHER INFORMATION

 Contact: Technical department                                                            Telephone: 847-559-2000

Old World Industries, Inc. makes no warranty, representation or guarantee as to the accuracy, sufficiency or completeness of the material set forth herein.  It is the user's responsibility to determine the safety, toxicity and suitability of his own use, handling and disposal of this product.  Since actual use by other is beyond our control, no warranty, expressed or implied, is made by Old World Industries, Inc. As to the effects of such use, the results to be obtained or the safety and toxicity of this product, nor does Old World Industries, Inc. Assume liability arising out of the use by others of this product referred to herein.  The date in the MSDS relates only to the specific material designated herein and does not relate to use in combination with any other material or in any process.